Pathophysiology 5th edition mccance

Life span content includes ten separate chapters for the pediatric content and special headings for aging content within the structures and functions chapters. Algorithms throughout the text illustrate the sequential progression of disease processes. Detailed chapter outlines with page numbers provide easy access to content and overview of topics.

Chapter introductions provide a rationale for learning the content about to be presented. Consistent presentation of each disease includes epidemiology, pathophysiology, clinical manifestations, and evaluation and treatment. Key terms are highlighted in each chapter and listed with page numbers for easy reference and chapter review.

Chapter summaries provide concise synopses of key points and serve as a built-in content review. An "Introduction to Pathophysiology" provides an entrance to the study of disease and defines basic terms. More than 90 "What's New? Includes approximately new full-color illustrations. Now includes a comprehensive glossary of approximately 1, terms to help students with the often difficult terminology related to pathophysiology.

Infection content is presented in a separate chapter to better organize content on mechanisms of self-defense. Extensive revisions and updates of every chapter, particularly: inflammation and immunity, stress, cancer, pain, the reproductive system, and urinary and renal systems alterations.

Authoritative content, outstanding illustrations, and extensive pediatric material make McCance the leading pathophysiology resource in the market. Convert currency. Add to Basket. Book Description Condition: New. Satisfaction Guaranteed! Alterations in extracellular matrix that include: a. Decreased fibronectin b. Increased collagen c. Decreased elastin d. Increased glycoproteins ANS: A Reduced amounts of fibronectin are found in some types of cancerous cells, allowing cancer cells to travel, or metastasize.

Collagen provides strength, and its breakdown is associated with osteoarthritis, not cancer. Elastin is found in the lungs and allows tissues to stretch; it is not associated with cancerous cells. Decreased, not increased, glycoproteins are associated with cancerous cells. Which form of cell communication is used to relate to other cells in direct physical contact?

Cell junction b. Gap junction c. Desmosomes d. Tight junctions ANS: A Cell junctions hold cells together and permit molecules to pass from cell to cell. Gap junctions allow communication from the inside of one cell to the inside of another.

Desmosomes are not involved in communication, but allow cells to hold together. Tight junctions are barriers that prevent movement of some substances and leakages of others. Pancreatic beta cells secrete insulin, which inhibits secretion of glucagon from neighboring alpha cells. This action is an example of which of the following signaling types?

Paracrine b. Autocrine c. Neurohormonal d. Hormonal ANS: A Paracrine signaling involves the release of local chemical mediators that are quickly taken up, destroyed, or immobilized, as in the case of insulin and the inhibition of the secretion of glucagon. When cells produce signals that they themselves respond to, autocrine signaling is used. Neurohormonal signaling involves secretion of hormones into the bloodstream by neurosecretory hormones.

Hormonal signaling involves specialized endocrine cells that secrete hormone chemicals released by one set of cells that travel through the tissue through the bloodstream to produce a response in other sets of cells. In cellular metabolism, each enzyme has a high affinity for a: a. Solute b. Substrate c.

Receptor d. Ribosome ANS: B Each enzyme has a high affinity for a substrate, a specific substance converted to a product of the reaction. Solutes are small particles that pass through the cell membrane. A receptor is a site on the cell wall that allows transport into the cell. Ribosomes are located inside the cell and are not related to the work of enzymes.

An athlete runs a marathon, after which his muscles feel fatigued and unable to contract. The athlete asks the nurse why this happened.

How should the nurse respond? GTP b. AMP c. ATP d. GTP is involved in cell signaling, not muscle contraction. AMP is not involved in muscle contraction. GMP is not involved in muscle contraction. Which phase of catabolism produces the most ATP? Digestion b. Glycolysis c. Oxidation d. Larger molecules are broken down into smaller units during digestion; no ATP is produced during this cycle.

During glycolysis, two molecules of ATP are produced from each glucose molecule, but the most ATP is produced during the citric acid cycle. Oxidation is part of the glycolysis process and ATP is produced, but more ATP is produced during the citric acid cycle. A nurse is teaching the staff about the three phases of cellular catabolism.

Which of the following should the nurse include? Digestion, glycolysis and oxidation, and the citric acid cycle b. Diffusion, osmosis, and mediated transport c. S phase, G phase, and M phase d. Metabolic absorption, respiration, and excretion ANS: A Digestion, glycolysis and oxidation, and the citric acid cycle are the three phases of cellular catabolism.

Diffusion, osmosis, and mediated transport are parts of the movement of fluids in and out of cells. The S, G, and M phases are phases of cellular division, not catabolism. Metabolic absorption, respiration, and excretion are functions of the cell. A runner has depleted all the oxygen available for muscle energy. Which of the following will facilitate his continued muscle performance? Electron-transport chain b.

Aerobic glycolysis c. Anaerobic glycolysis d. The electron-transport chain is part of the citric acid cycle. Aerobic glycolysis involves the presence of oxygen. Oxidative phosphorylation is the mechanism by which the energy produced from carbohydrates, fats, and proteins is transferred to ATP. It is not part of muscle performance. The faculty member asked the student to identify the appropriate term for the movement of small, electrically uncharged molecules through a semipermeable barrier.

Which answer indicates the nursing student understood the teaching? Osmosis b. Diffusion c. Hydrostatic pressure d. Active transport ANS: B Diffusion is the movement of a solute molecule from an area of greater solute concentration to an area of lesser solute concentration.

Osmosis is the movement of water across a semipermeable membrane from a region of higher water concentration to one of lower concentration. Hydrostatic pressure is the force of fluid against a cell membrane. Within the vascular system, this pressure is the blood pressure. In active transport, molecules move up a concentration gradient. This process requires energy.

A nurse is teaching a patient about fluid and electrolytes. Which of the following indicates the teaching was successful regarding electrolytes? Electrolytes are: a. Small lipid-soluble molecules b. Large protein molecules c.

Micronutrients used to produce ATP d. Electrolytes are not lipid soluble. Electrolytes are not made up of protein. Electrolytes do not have a role in the production of ATP. A nurse is reading a chart and sees the term oncotic pressure.

Cancer in Children. Structure and Function of the Neurologic System Alterations of Neurologic Function in Children. Mechanisms of Hormonal Regulation Alterations of Hormonal Regulation Structure and Function of the Reproductive Systems Alterations of the Female Reproductive System Alterations of the Male Reproductive System Sexually Transmitted Infections.

Structure and Function of the Hematologic System Alterations of Erythrocyte, Platelet, and Hemostatic Function Alterations of Leukocyte and Lymphoid Function Alterations of Hematologic Function in Children. Structure and Function of the Cardiovascular and Lymphatic Systems Alterations of Cardiovascular Function Alterations of Cardiovascular Function in Children.

Structure and Function of the Pulmonary System Alterations of Pulmonary Function Alterations of Pulmonary Function in Children.